Frequency of chromosomal trisomies and risk factors

Research output: Contribution to journalArticle

Abstract

The aim of the study is to evaluate the use of cytogenetic and molecular cytogenetic techniques to prenatal trisomies setting 13 , 18 and 21 of chromosomes for patients during the 2007 to 2011, that had genetic counseling to determine between these trisomies and risk factors.1,156 patients were examined and for 49 (4.2%), abnormal karyotype was identified, of which 30 (61%) are associated with Down syndrome, 14 (29%) to the Edwards syndrome and 5 (10%) are those relating to Patau syndrome. After studying questionnaires and case records data, based on the statistical reliability of the data analysis of fetal abnormality association with the main factors on reproductive (abortions, contraceptives) and other risks or environmental factors (smoking, genetic diseases and drug abuse) was performed.
Original languageEnglish
Pages (from-to)218-221
JournalInternational journal of current pharmaceutical & clinical research
Volume5
Issue number4
Publication statusPublished - 2015

Fingerprint

Trisomy
Down Syndrome
Abnormal Karyotype
Chromosomes, Human, Pair 18
Statistical Data Interpretation
Inborn Genetic Diseases
Cytogenetic Analysis
Genetic Counseling
Contraceptive Agents
Cytogenetics
Substance-Related Disorders
Smoking
Trisomy 13 syndrome
Surveys and Questionnaires
Trisomy 18

Keywords

  • Chromosomes
  • Genetic testing
  • Prenatal

Cite this

Frequency of chromosomal trisomies and risk factors. / Serapinas, Danielius.

In: International journal of current pharmaceutical & clinical research, Vol. 5, No. 4, 2015, p. 218-221.

Research output: Contribution to journalArticle

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